Publications and Presentations

Verity Software House has a rich heritage of research publications in the field of flow cytometry.  This page lists a few of the publications to which Verity has contributed.  Where possible, we have provided links to the periodicals listed.

We also produce white papers and lecture notes on a broad range of topics in flow cytometry.  These are available directly from this site.

Recent Presentations and Posters
A Novel Modeling System for Analysis of High Dimensional data: Definition of T-cell Effector and Memory Subsets Using GemStone Software	This poster by Inokuma, Trotter, et al, explores the use of GemStone for analyzing high-dimensional T-Cell data. Presented at the CYTO 2010 conference in Seattle, WA, USA.
Improved algorithms for the analysis and classification of HbF-containing Red Blood Cells	This poster by Davis, Hunsberger, et al, compares traditional analysis approaches with GemStone analysis for Fetal Maternal Hemorrhage. Presented at the CYTO 2010 conference in Seattle, WA, USA.
Multi-parametric Cell Cycle Analysis: A comparison of transition state-related cluster and probability state analyses	This poster by Bray, Bagwell, et al, compares GemStone state analysis with a gate-based analysis of DNA, cyclins A2 and B1, and phospho-S10-histone H3. Presented at the CYTO 2010 conference in Seattle, WA, USA.
Probability State Modeling Analysis of CD38, CD10, and CD19 Up-regulation in Early Human B-Cell Development	In this poster by Bagwell, Stewart, et al, Probability State Modeling was used to determine the relative order of CD38, CD19, and CD10 up-regulation for a number of uninvolved bone marrow specimens. Presented at the CYTO 2010 conference in Seattle, WA, USA.

 

White Papers, Lectures, Pre-prints
Polychromatic flow cytometry: A rapid method for the reduction and analysis of complex multiparameter data	This paper by Petrausch, Haley, et al, describes a powerful multiparameter analysis approach using WinList's FCOM function to reduce greatly the complexity of analyzing high-dimensional data.
HyperLogTM - A Flexible Log-like Transform for Negative, Zero, and Positive Valued Data	Pre-print of a peer-reviewed article in Cytometry 2005, focused on ways to display data for flow cytometry.
A Journey Through Flow Cytometric Immunofluorescence Analysis	Pre-print of article by C. Bruce Bagwell from Clinical Immunology Newsletter, Vol 16, Number 3, 1996
Super Enhanced D-Value	The mathematics behind the Super Enhanced D-Value (SED) calculation.
Using FCOM for Subset Analysis	Explains this easy-to-use WinList feature
Enhanced Proliferation Analysis	Integrates WinList and ModFit LT
Effects of Resolution Reduction on Data Analysis	Pre-print of a peer-reviewed article in Cytometry 2003, describing a new resolution reduction algorithm
Linear to Log Data Conversions	Explores linear-to-log data conversions in WinList
Examination of DNA Guidelines	Examines several critical criteria for DNA analysis

 

A Sampling of Peer-Reviewed Publications

Contact us for a more complete listing.

DNA/Cell Cycle Analysis As Prognostic Indicators in Breast Tumors Revisited, 
Clinics in Laboratory Medicine, 2001.

Optimizing Flow Cytometric DNA Ploidy and S-Phase Fraction 
as Independent Prognostic Markers for Node-Negative Breast Cancer Specimens,
Communications in Clinical Cytometry, Vol 46:3, pps 121-135, 2001.

Data File Standard for Flow Cytometry, Version FCS3.0,
Cytometry Originally in 1990 ;11(3):323-32, Version 3.0 in 1996.

Fetal RBC detection,
Laboratory Hematology 2:49, 1996.

Flow cytometric detection of fetal hemoglobin (Hb F) containing red blood cells,
International Journal of Hematology 64:S157, 1996.

A Journey through Flow Cytometric Immunofluorescence Analyses - 
Finding Accurate and Robust Algorithms that Estimate Positive Fraction Distributions, 
Clinical Immunology Newsletter, Vol. 16, No. 3, 1996.

A new homogeneous assay system for specific nucleic acid sequences: poly-dA and poly-A detection, 
Nucleic Acids Research, Vol: 22, No. 12, 242-2425, 1994.

Guidelines for implementation of clinical DNA cytometry, 
Cytometry, 14(5):472-7, 1993.

Software Spectral Overlap Compensation For Any Number of Flow Cytometry Parameters, 
New York Academy of Sciences, .20(677):167-84,1993.

Parathyroid carcinoma: the relationship of nuclear DNA content to clinical outcome,
Surgery, 113(3):290-6, 1993.

DNA signal splitting improves detection and analysis of tetraploid populations, 
Cytometry, 13(7):787-9, 1992.

DNA Histogram Debris Theory and Compensation, 
Cytometry. 12:107-118, 1991.

 

Presentations

The HyperLog™ Transformation for Compensated Data
Presented at the 28th Annual Course in Flow Cytometry, Los Alamos, NM, USA
June, 2005

Displaying Flow Data
Presented at the Clinical Flow Cytometry Course, XVII, Pittsburgh, Pennsylvania, USA
September, 2004

Compensation Basics
Presented at ISAC XXII Congress, Montpellier, France, 
May, 2004

Breast CA Prognosis 
Presented at 27th Annual Course in Flow Cytometry, Bowdoin College, Maine, USA
June, 2004